BiochemProbe — Life Science Research Reagents

PH-HG-005-5 free base

PH-HG-005-5 (compound 16c) is a derivative of SN-38 and can be used as Drug-Linker Conjugates for ADC.

For research use only. Not for human or veterinary use.

Research area Cancer
Purity >98% Stock Inquire

PH-HG-005-5 structure

CAS No.: 2810895-93-1

Download structure (.mol)

Pack sizes & pricing

Size Price SKU Stock
25 mg USD 620.00 BP-02171-25mg In stock Get quote
50 mg USD 980.00 BP-02171-50mg In stock Get quote
100 mg USD 1,560.00 BP-02171-100mg In stock Get quote
250 mg USD 3,150.00 BP-02171-250mg In stock Get quote

Need another size or custom synthesis? Request a quote.

Description

PH-HG-005-5 (compound 16c) is a derivative of SN-38 and can be used as Drug-Linker Conjugates for ADC. PH-HG-005-5 can conjugate to targeting peptides for ADCs synthesis .

Identifiers

SMILES
CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)OC(=O)OCC5=CC=C(C=C5)NC(=O)[C@H](CCCNC(=O)N)NC(=O)[C@H](C(C)C)N)C2=NC6=C1C=C(C=C6)O
InChIKey
QTKSYHWJQGUBIT-XWFQJVGVSA-N

Specifications

MW (average)
797.8528
Formula
C41H47N7O10
CAS No.
2810895-93-1
Physical state
Solid
Color
Light yellow to yellow
Shipping
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage
Powder -20℃, sealed storage, away from moisture and light, 2 years; In solvent -20℃ 1 month;

Solubility

Soluble in DMSO

References

[1]. Chen Jian, et al. EphA2 bicyclic peptide ligand and conjugate thereof. World Intellectual Property Organization, WO2023061482 A1. 2023-04-20.

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