SLF-amido-C2-COOH free base

SLF-amido-C2-COOH is a synthetic ligand.

For research use only. Not for human or veterinary use.

Target Ligands for Target Protein for PROTAC FKBP

Research area Cancer

Purity >98% Stock Inquire

Data Sheet SDS COA

SLF-amido-C2-COOH structure

CAS No.: 1092369-24-8

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
25 mg	USD 410.00	BP-00019-25mg	In stock	Get quote
50 mg	USD 660.00	BP-00019-50mg	In stock	Get quote
100 mg	USD 1,050.00	BP-00019-100mg	In stock	Get quote
250 mg	USD 2,010.00	BP-00019-250mg	In stock	Get quote
500 mg	USD 3,360.00	BP-00019-500mg	In stock	Get quote
1 g	USD 5,540.00	BP-00019-1g	In stock	Get quote

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Description

SLF-amido-C2-COOH (PROTAC FKBP12-binding moiety 1) is a synthetic ligand for FKBP (SLF). SLF-amido-C2-COOH (PROTAC FKBP12-binding moiety 1) can be used in the synthesis of PROTACs.

Biological activity

In Vitro SLF-amido-C2-COOH (PROTAC FKBP12-binding moiety 1) is a synthetic ligand for FKBP (SLF). SLF is composed of only one half of FK506 and it is known to have a significantly weaker affinity for FKBP12.

Identifiers

SMILES: [C@@H](OC(=O)[C@H]1N(C(C(C(CC)(C)C)=O)=O)CCCC1)(CCC2=CC(OC)=C(OC)C=C2)C3=CC(NC(CCC(O)=O)=O)=CC=C3
InChIKey: FTAKPNRZIJEFIG-IZZNHLLZSA-N

Specifications

MW (average): 624.7212
Formula: C₃₄H₄₄N₂O₉
CAS No.: 1092369-24-8
Physical state: Solid
Color: Off-white to light yellow
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20°C, 3 years , 4°C, 2 years; In solvent -20℃ 1 month;

Solubility

Soluble in DMSO : 100 mg/mL

Documents

References

[1]. Dunyak BM, et al. Selective Targeting of Cells via Bispecific Molecules That Exploit Coexpression of TwoIntracellular Proteins. ACS Chem Biol. 2015 Nov 20;10(11):2441-7.

Same target

Search Ligands for Target Protein for PROTAC

Same research area

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