2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan free base

2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan is a drug-linker conjugates for ADC, consiting of a cleavable linker and Exatecan.

For research use only. Not for human or veterinary use.

Target Drug-Linker Conjugates for ADC Topoisomerase

Research area Cancer

Purity >98% Stock Inquire

Data Sheet SDS COA

2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan structure

CAS No.: 2964536-59-0

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
10 mg	USD 498.00	BP-02389-10mg	In stock	Get quote
25 mg	USD 922.00	BP-02389-25mg	In stock	Get quote
50 mg	USD 1,348.00	BP-02389-50mg	In stock	Get quote
100 mg	USD 2,198.00	BP-02389-100mg	In stock	Get quote
250 mg	Inquire	BP-02389-250mg	In stock	Inquire
500 mg	Inquire	BP-02389-500mg	In stock	Inquire

Need another size or custom synthesis? Request a quote.

Description

2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan is a drug-linker conjugates for ADC, consiting of a cleavable linker and Exatecan. 2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-Exatecan can be linked to anti-Her3 antibody .

Biological activity

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Identifiers

SMILES: N(C(COCNC(CNC([C@H](CC1=CC=CC=C1)NC(CNC(CNC(CCCC#CC=2C=NC(S(C)(=O)=O)=NC2)=O)=O)=O)=O)=O)=O)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(F)C8
InChIKey: NHWYUGQZZZWOGL-JWSBGTHYSA-N

Specifications

MW (average): 1091.1260
Formula: C₅₃H₅₅FN₁₀O₁₃S
CAS No.: 2964536-59-0
Physical state: Solid
Color: Light yellow to yellow
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20℃, sealed storage, away from moisture and light, 2 years; In solvent -20℃ 1 month;

Solubility

Soluble in DMSO

In vitro: DMSO : ≥ 100 mg/mL

Documents

References

[1]. Cai JQ, et al. Antibody against her3, conjugate and use thereof. WO2023143263A1. 2023-08-03.

Same target

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Same research area

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