Exatecan-amide-cyclopropanol free base

Exatecan-amide-cyclopropanol (compound 1) is a anticancer agent.

For research use only. Not for human or veterinary use.

Target ADC Payloads Topoisomerase

Research area Cancer

Purity >98% Stock Inquire

Data Sheet SDS COA

Exatecan-amide-cyclopropanol structure

CAS No.: 2414254-34-3

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
25 mg	USD 475.00	BP-02438-25mg	In stock	Get quote
50 mg	USD 760.00	BP-02438-50mg	In stock	Get quote
100 mg	USD 1,210.00	BP-02438-100mg	In stock	Get quote
250 mg	USD 2,430.00	BP-02438-250mg	In stock	Get quote
500 mg	USD 3,890.00	BP-02438-500mg	In stock	Get quote
1 g	Inquire	BP-02438-1g	In stock	Inquire

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Description

Exatecan-amide-cyclopropanol (compound 1) is a anticancer agent. Exatecan-amide-cyclopropanol shows anti-proliferation activity against SK-BR-3 and U87 cells, with IC50 values of 0.12 and 0.23 nM, respectively .

Identifiers

SMILES: O=C(C1(CC1)O)N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73
InChIKey: YBPWXIPEPLZSMS-JMQGSBJISA-N

Specifications

MW (average): 519.5209
Formula: C₂₈H₂₆FN₃O₆
CAS No.: 2414254-34-3
Physical state: Solid
Color: Light yellow to yellow
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: -20°C, sealed storage, away from moisture

Solubility

Soluble in DMSO : 2.73 mg/mL

Documents

References

[1].Xu Jianyan, et al. Ligand-drug conjugate of exatecan analogue, preparation method therefor and application thereof. WO2020063676A1.

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