9-Chloromethyl-10-hydroxy-11-F-Camptothecin free base

9-Chloromethyl-10-hydroxy-11-F-Camptothecin is a novel camptothecin derivatives.

For research use only. Not for human or veterinary use.

Target Topoisomerase

Research area Cancer

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Data Sheet SDS COA

9-Chloromethyl-10-hydroxy-11-F-Camptothecin structure

CAS No.: 2414594-22-0

Download structure (.mol)

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Description

9-Chloromethyl-10-hydroxy-11-F-Camptothecin is a novel camptothecin derivatives. 9-Chloromethyl-10-hydroxy-11-F-Camptothecin is a DNA topoisomerase I (Topo I) inhibitor, can be used in anticancer research.

Identifiers

SMILES: O=C1N2C(C=3C(C2)=C(CCl)C=4C(N3)=CC(F)=C(C)C4)=CC5=C1COC(=O)[C@@]5(CC)O
InChIKey: VIMRBMFQCXMCKY-QFIPXVFZSA-N

Specifications

MW (average): 428.8410
Formula: C₂₂H₁₈ClFN₂O₄
CAS No.: 2414594-22-0
Physical state: Solid
Color: White to off-white
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Documents

References

[1]. Chari Ravi, et al. Preparation of camptothecin derivatives as antitumor agents. WO2020219287 A1. 2020-10-29

Same target

Search Topoisomerase

Same research area

Search Cancer