E3 ligase Ligand 43 free base
E3 ligase Ligand 43 serves as the E3 ubiquitin ligase ligand for ACBI3.
For research use only. Not for human or veterinary use.
Target
Ligands for E3 Ligase
Research area
Cancer
Purity >98%
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E3 ligase Ligand 43 structure
CAS No.: 2821795-71-3
Pack sizes & pricing
Description
E3 ligase Ligand 43 serves as the E3 ubiquitin ligase ligand for ACBI3. E3 ligase Ligand 43 can be utilized for the synthesis of PROTACs.
Identifiers
- SMILES
-
[N-]=[N+]=N[C@@H](C(C)C)C(N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C3=C(N=CS3)C)C=C2)CO)=O)=O - InChIKey
-
SWCBBOKZVRSTHO-XWSJACJDSA-N
Specifications
- MW (average)
- 472.5610
- Formula
- C22H28N6O4S
- CAS No.
- 2821795-71-3
- Physical state
- Solid
- Color
- White to off-white
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- Please store the product under the recommended conditions in the Certificate of Analysis.
Solubility
Soluble in DMSO
Documents
References
[1]. Popow J, et al. Targeting cancer with small-molecule pan-KRAS degraders[J]. Science, 2024, 385(6715): 1338-1347.
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