E3 ligase Ligand 18 free base
E3 ligase Ligand 18 is a ligand for E3 ubiquitin ligase.
For research use only. Not for human or veterinary use.
Target
Ligands for E3 Ligase
Research area
Cancer
Purity >98%
Stock Inquire
E3 ligase Ligand 18 structure
CAS No.: 2241669-88-3
Pack sizes & pricing
| Size | Price | SKU | Stock | |
|---|---|---|---|---|
| 250 mg | USD 480.00 | BP-02198-250mg | In stock | Get quote |
| 500 mg | USD 760.00 | BP-02198-500mg | In stock | Get quote |
| 1 g | USD 1,230.00 | BP-02198-1g | In stock | Get quote |
| 2 g | USD 1,950.00 | BP-02198-2g | In stock | Get quote |
| 3 g | USD 2,350.00 | BP-02198-3g | In stock | Get quote |
| 5 g | USD 3,120.00 | BP-02198-5g | In stock | Get quote |
Need another size or custom synthesis? Request a quote.
Description
E3 ligase Ligand 18 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 18 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
Identifiers
- SMILES
-
CC(N[C@H](C(O)=O)CSC1=NC(C(N=C(N2)N)=O)=C2N1CC3=CC=C(C=C3)Cl)=O - InChIKey
-
CEOFSRBWEZNKGM-NSHDSACASA-N
Specifications
- MW (average)
- 436.8730
- Formula
- C17H17ClN6O4S
- CAS No.
- 2241669-88-3
- Physical state
- Solid
- Color
- White to off-white
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- Powder 4°C, sealed storage, away from moisture; In solvent -20°C, 1 month;
Solubility
soluble in DMSO
Documents
References
[1]. Heterocyclic compound. WO2018143403A1.
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