GSK-F1 free base
GSK-F1 is an orally active PI4KA inhibitor.
For research use only. Not for human or veterinary use.
GSK-F1 structure
CAS No.: 1402345-92-9
Pack sizes & pricing
| Size | Price | SKU | Stock | |
|---|---|---|---|---|
| 25 mg | USD 420.00 | BP-02190-25mg | In stock | Get quote |
| 50 mg | USD 660.00 | BP-02190-50mg | In stock | Get quote |
| 100 mg | USD 1,050.00 | BP-02190-100mg | In stock | Get quote |
| 250 mg | USD 2,150.00 | BP-02190-250mg | In stock | Get quote |
| 500 mg | USD 3,440.00 | BP-02190-500mg | In stock | Get quote |
Need another size or custom synthesis? Request a quote.
Description
GSK-F1 (Compound F1) is an orally active PI4KA inhibitor with pIC50 values of 8.0, 5.9, 5.8, 5.9, 5.9 and 6.4 against PI4KA, PI4KB, PI3KA, PI3KB, PI3KG and PI3KD, respectively. GSK-F1 can be used for HCV infection research .
Biological activity
In Vivo GSK-F1 (3-40 mg/kg/day; p.o.; twice daily; up to 14 days) causes death in some mice and adverse reactions such as gastrointestinal abnormalities in surviving mice.
Identifiers
- SMILES
-
O=S(C1=CC(C2=CC3=C(N=C(N)N(C4=CC=CC=C4C(F)(F)F)C3=O)C=C2)=CN=C1OC)(NC5=CC=C(F)C=C5F)=O - InChIKey
-
MSRFVAYVUUHQCN-UHFFFAOYSA-N
Specifications
- MW (average)
- 603.5200
- Formula
- C27H18F5N5O4S
- CAS No.
- 1402345-92-9
- Physical state
- Solid
- Color
- White to off-white
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- Powder -20°C, sealed storage, away from moisture and light; In solvent -20℃, 1 month;
Solubility
soluble in DMSO