Oteseconazole free base · Synonyms: VT-1161
Oteseconazole (VT-1161) is an orally active anti-fungal agent, potently binds to and inhibits Candida albicans CYP51 (Kd, <39 nM), shows no obvious…
For research use only. Not for human or veterinary use.
Oteseconazole structure
CAS No.: 1340593-59-0
Pack sizes & pricing
| Size | Price | SKU | Stock | |
|---|---|---|---|---|
| 500 mg | USD 580.00 | BP-01870-500mg | In stock | Get quote |
| 1 g | USD 1,080.00 | BP-01870-1g | In stock | Get quote |
| 5 g | Inquire | BP-01870-5g | Inquire | Inquire |
Need another size or custom synthesis? Request a quote.
Description
Oteseconazole (VT-1161) is an orally active anti-fungal agent, potently binds to and inhibits Candida albicans CYP51 (Kd, <39 nM), shows no obvious effect on human CYP51.
Biological activity
Oteseconazole (5-25 mg/kg, p.o., daily, 9 days) effectively inhibits mycological growth and improves the clinical signs of infection in guinea pigs infected with T. mentagrophytes
Identifiers
- SMILES
-
O[C@@](CN1C=NN=N1)(C(C=CC(F)=C2)=C2F)C(F)(C3=CC=C(C4=CC=C(OCC(F)(F)F)C=C4)C=N3)F - InChIKey
-
IDUYJRXRDSPPRC-NRFANRHFSA-N
Specifications
- MW (average)
- 527.3943
- Formula
- C23H16F7N5O2
- CAS No.
- 1340593-59-0
- Physical state
- Solid
- Color
- White to off-white
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Solubility
Soluble in DMSO : 175 mg/mL