BiochemProbe — Life Science Research Reagents

Ziresovir free base · Synonyms: RO-0529 | AK0529

Ziresovir is a potent, selective, and orally bioavailable respiratory syncytial virus fusion protein protein inhibitor.

For research use only. Not for human or veterinary use.

Target RSV
Research area Infection
Purity >98% Stock Inquire

Ziresovir structure

CAS No.: 1422500-60-4

Download structure (.mol)

Pack sizes & pricing

Size Price SKU Stock
50 mg USD 800.00 BP-00892-50mg In stock Get quote
100 mg USD 1,100.00 BP-00892-100mg In stock Get quote
250 mg USD 1,900.00 BP-00892-250mg In stock Get quote
500 mg USD 3,298.00 BP-00892-500mg In stock Get quote
1 g Inquire BP-00892-1g In stock Inquire

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Description

Ziresovir (AK0529;RO-0529) is a potent, selective, and orally bioavailable respiratory syncytial virus (RSV) fusion (F) protein (RSV F) protein inhibitor. Ziresovir shows anti-RSV activity (EC50=3 nM) and highlights pharmacokinetics in animal species .

Biological activity

Ziresovir (AK0529;RO-0529) is a potent, selective, and orally bioavailable respiratory syncytial virus (RSV) fusion (F) protein (RSV F) protein inhibitor. Ziresovir shows anti-RSV activity (EC50=3 nM) and highlights pharmacokinetics in animal species.

Identifiers

SMILES
O=S1(=O)C=2C=CC=CC2CN(C=3N=C4C=CC(=CC4=C(N3)NCC5(N)COC5)C)CC1
InChIKey
GAAICKUTDBZCMT-UHFFFAOYSA-N

Specifications

MW (average)
439.5310
Formula
C22H25N5O3S
CAS No.
1422500-60-4
Physical state
Solid
Color
White to off-white
Shipping
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage
Powder -20℃ 3 years, 4℃ 2 years; In solvent -20℃ 1 year;

Solubility

Soluble in DMSO

In vitro
DMSO : 125 mg/mL

References

[1]. Zheng X, et al. Discovery of Ziresovir as a Potent, Selective, and Orally Bioavailable Respiratory Syncytial Virus Fusion Protein Inhibitor. J Med Chem. 2019 Jul 11;62(13):6003-6014.

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