CCR1 antagonist 8 free base

BI 639667, a chemical probe, is a CCR1 antagonist.

For research use only. Not for human or veterinary use.

Target CCR

Research area Inflammation/Immunology Endocrinology

Purity >98% Stock Inquire

Data Sheet SDS COA

CCR1 antagonist 8 structure

CAS No.: 1295298-26-8

Pack sizes & pricing

Size	Price	SKU	Stock
10 mg	USD 550.00	BP-02186-10mg	In stock	Get quote
25 mg	USD 1,100.00	BP-02186-25mg	In stock	Get quote
50 mg	USD 1,750.00	BP-02186-50mg	In stock	Get quote
100 mg	USD 2,800.00	BP-02186-100mg	In stock	Get quote

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BI 639667 (compound 19n), a chemical probe, is a CCR1 antagonist, with an IC50 of 1.8 nM in Ca 2+ flux assay .

SMILES: O=C(C1=CN=CC2=C1C=NN2C3=CC=C(F)C=C3)NC4(C5=CC(S(=O)(C)=O)=NC=C5)CC4
InChIKey: PXQATVYJKMMHAU-UHFFFAOYSA-N

MW (average): 451.4730
Formula: C₂₂H₁₈FN₅O₃S
CAS No.: 1295298-26-8
Physical state: Solid
Color: White to off-white
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20℃ 3 years; 4℃ 2 years; In solvent -20℃ 1 year;

soluble in DMSO

[1]. Harcken C, et al. Identification of novel azaindazole CCR1 antagonist clinical candidates. Bioorg Med Chem Lett. 2019 Feb 1;29(3):441-448.

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