Clobutinol free base
Clobutinol is a compound that has anti-tussive effects.
For research use only. Not for human or veterinary use.
Clobutinol structure
CAS No.: 14860-49-2
Pack sizes & pricing
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Description
Clobutinol is a compound that has anti-tussive effects. Clobutinol affects heart rate and blood pressure, it can be used for cough related research.
Biological activity
In Vitro Clobutinol (10 μM) significantly inhibits the voltage-gated outward current in hERG-expressing cells[1]. Clobutinol (0-1000 μM) inhibits the outward current in hERG transfected cells with an IC50 value of 1.9 μM In Vivo Clobutinol (1-20 mg/kg; i.v. once) has no obvious effect on the airway of guinea-pigs. Clobutinol (1 and 10 mg/kg; i.v. once) affects heart rate and mean blood pressure of guinea pigs
Identifiers
- SMILES
-
ClC1=CC=C(C=C1)CC(O)(C)C(C)CN(C)C - InChIKey
-
KVHHQGIIZCJATJ-UHFFFAOYSA-N
Specifications
- MW (average)
- 255.7840
- Formula
- C14H22ClNO
- CAS No.
- 14860-49-2
- Physical state
- Solid
- Color
- White to off-white
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- Please store the product under the recommended conditions in the Certificate of Analysis.