Oditrasertib free base · Synonyms: DNL788 | SAR443820
Oditrasertib is an orally active, BBB-penatrable and selective reversible inhibitor of RIPK1.
For research use only. Not for human or veterinary use.
Oditrasertib structure
CAS No.: 2252271-93-3
Pack sizes & pricing
| Size | Price | SKU | Stock | |
|---|---|---|---|---|
| 50 mg | USD 420.00 | BP-00101-50mg | In stock | Get quote |
| 100 mg | USD 578.00 | BP-00101-100mg | In stock | Get quote |
| 250 mg | USD 885.00 | BP-00101-250mg | In stock | Get quote |
| 500 mg | USD 1,195.00 | BP-00101-500mg | In stock | Get quote |
| 1 g | USD 1,650.00 | BP-00101-1g | In stock | Get quote |
Need another size or custom synthesis? Request a quote.
Description
Oditrasertib (SAR443820) is an orally active, BBB-penatrable and selective reversible inhibitor of RIPK1. Oditrasertib can be used in the research of chronic inflammatory central nervous system diseases, such as amyotrophic lateral sclerosis and multiple sclerosis.
Biological activity
In Vitro Oditrasertib has a 50% inhibitory concentration of 3.16 nM in human PBMCs and 1.6 nM in iPSC-derived microglia.
Specifications
- MW (average)
- 295.2846
- Formula
- C14H15F2N3O2
- CAS No.
- 2252271-93-3
- Physical state
- Solid
- Color
- white to off-white
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- Powder 4℃ 2 years; In solvent -20℃ 1 month;
Solubility
Soluble in DMSO