DOPEXAMINE free base

Dopexamine is a β2 adrenergic receptor agonist.

For research use only. Not for human or veterinary use.

Target Adrenergic Receptor

Research area Cardiovascular Disease Endocrinology

Purity >98% Stock Inquire

Data Sheet SDS COA

DOPEXAMINE structure

CAS No.: 86197-47-9

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
10 mg	USD 480.00	BP-00009-10mg	In stock	Get quote
25 mg	USD 950.00	BP-00009-25mg	In stock	Get quote
50 mg	USD 1,500.00	BP-00009-50mg	In stock	Get quote
100 mg	USD 2,400.00	BP-00009-100mg	In stock	Get quote
250 mg	USD 4,600.00	BP-00009-250mg	In stock	Get quote
500 mg	USD 7,500.00	BP-00009-500mg	In stock	Get quote
1 g	Inquire	BP-00009-1g	In stock	Inquire

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Description

Dopexamine is a β2 adrenergic receptor agonist.

Biological activity

In Vitro Dopexamine is a dopamine analogue with agonist activity at β2 and dopaminergic receptors. Dopexamine can attenuate the systemic inflammatory response, reduce tissue leukocyte infiltration, and protect against organ injury at doses that do not alter global hemodynamics or regional microvascular flow[1]. Dopexamine is a dopamine analog that stimulates β-adrenergic and dopamine 1 and 2 receptors, conferring some vasodilatory effects. Dopexamine reduces the systemic inflammatory response to endotoxin, including cytokine release, endothelial adhesion molecules, and oxidative stress, without substantially changing systemic hemodynamics, either blood pressure or stroke volume.

Identifiers

SMILES: OC1=CC=C(C=C1O)CCNCCCCCCNCCC=2C=CC=CC2
InChIKey: RYBJORHCUPVNMB-UHFFFAOYSA-N

Specifications

MW (average): 356.5017
Formula: C₂₂H₃₂N₂O₂
CAS No.: 86197-47-9
Physical state: Solid
Color: White to off-white
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Documents

References

[1]. Bangash MN, et al. Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow. Crit Care. 2013 Mar 28;17(2):R57.

[2]. Hollenberg SM. Dopexamine: immunomodulatory, hemodynamic, or both? Crit Care. 2013 May 13;17(3):143.

Same target

Search Adrenergic Receptor

Same research area

Search Cardiovascular Disease