MCB-613 free base · Synonyms: MCB 613 · MCB613

MCB-613 is a potent Steroid receptor coactivator SRC small molecule stimulator.

For research use only. Not for human or veterinary use.

Target Reactive Oxygen Species (ROS) Paraptosis

Research area Cancer

Purity >98% Stock Inquire

Data Sheet SDS COA

MCB-613 structure

CAS No.: 1162656-22-5

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
100 mg	USD 380.00	BP-01846-100mg	In stock	Get quote
250 mg	USD 580.00	BP-01846-250mg	In stock	Get quote
500 mg	USD 830.00	BP-01846-500mg	In stock	Get quote
1 g	USD 1,150.00	BP-01846-1g	In stock	Get quote

Need another size or custom synthesis? Request a quote.

Description

MCB-613 is a potent Steroid receptor coactivator SRC small molecule stimulator.

Biological activity

MCB-613 is a potent Steroid receptor coactivator SRC small molecule 'stimulator' (SMS), super-stimulates SRCs' transcriptional activity. MCB-613 increases SRCs' interactions with other coactivators and markedly induces ER stress coupled to the generation of reactive oxygen species (ROS). MCB-613 is a SMS that target oncogenes can be exploited as anti-cancer agents by over-stimulating the SRC oncogenic program.

Identifiers

SMILES: CCC1C\C(C(=O)\C(C1)=C\C1=CN=CC=C1)=C/C1=CN=CC=C1
InChIKey: MMBSCBVEHMETSA-GDAWTGGTSA-N

Specifications

MW (average): 304.3856
Formula: C₂₀H₂₀N₂O
CAS No.: 1162656-22-5
Physical state: Solid
Color: light yellow to yellow
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20℃ 2 years; In solvent -20℃ 1 month;

Solubility

Soluble in DMSO

Documents

References

[1]. Wang L, et al. Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death. Cancer Cell. 2015 Aug 10;28(2):240-52.

Same target

Search Reactive Oxygen Species (ROS)

Same research area

Search Cancer