ZSA-51 free base · Synonyms: ZSA 51 · ZSA51

ZSA-51 is a potent and orally active STING agonist.

For research use only. Not for human or veterinary use.

Target STING

Research area Cancer

Purity >98% Stock Inquire

Data Sheet SDS COA

ZSA-51 structure

CAS No.: 3084542-49-1

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
100 mg	USD 585.00	BP-02273-100mg	In stock	Get quote
250 mg	USD 900.00	BP-02273-250mg	In stock	Get quote
500 mg	USD 1,250.00	BP-02273-500mg	In stock	Get quote
1 g	USD 1,950.00	BP-02273-1g	In stock	Get quote
5 g	Inquire	BP-02273-5g	In stock	Inquire

Need another size or custom synthesis? Request a quote.

Description

ZSA-51 is a potent and orally active STING agonist. ZSA-51 shows anticancer activity. ZSA-51 remodeles immune microenvironment both in tumor and lymph node.

Identifiers

SMILES: COC(CCN1C(C2=C(C3=CC(OC)=C(C=C3S2)OC)C1=O)=O)=O
InChIKey: RTHGCGQMIJRVFB-UHFFFAOYSA-N

Specifications

MW (average): 349.3580
Formula: C₁₆H₁₅NO₆S
CAS No.: 3084542-49-1
Physical state: Solid
Color: Light yellow to yellow
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder 4℃, sealed storage, away from moisture, 2 years; In solvent -20℃ 1 month;

Solubility

Soluble in DMSO

In vitro: DMSO : 6.67 mg/mL

Documents

References

[1]. Zhao HY, et al. An oral tricyclic STING agonist suppresses tumor growth through remodeling of the immune microenvironment. Cell Chem Biol. 2025 Jan 24:S2451-9456(25)00004-2.

Same target

Search STING

Same research area

Search Cancer