Minzasolmin free base · Synonyms: UCB0599 | (R)-NPT200-11
Minzasolmin is an alpha-synuclein oligomerization inhibitor.
For research use only. Not for human or veterinary use.
Minzasolmin structure
CAS No.: 1802518-92-8
Pack sizes & pricing
| Size | Price | SKU | Stock | |
|---|---|---|---|---|
| 5 mg | USD 425.00 | BP-01930-5mg | In stock | Get quote |
| 10 mg | USD 685.00 | BP-01930-10mg | In stock | Get quote |
| 25 mg | USD 1,045.00 | BP-01930-25mg | In stock | Get quote |
| 50 mg | USD 1,585.00 | BP-01930-50mg | In stock | Get quote |
| 100 mg | USD 2,285.00 | BP-01930-100mg | In stock | Get quote |
| 500 mg | Inquire | BP-01930-500mg | Inquire | Inquire |
Need another size or custom synthesis? Request a quote.
Description
Minzasolmin is an alpha-synuclein oligomerization inhibitor.
Biological activity
In Vivo Minzasolmin (1 mg/kg, 5 mg/kg; intraperitoneal injection; once a day, 5 days a week; 3 months) significantly improves motor coordination ability (such as prolonged rotarod test time), reduces α-synuclein (α-Syn) pathological deposition and neuroinflammatory markers (such as reduced IL-6 levels) in the cerebral cortex and hippocampus, and restores striatal dopamine transporter (DAT) levels in the Thy1-αSyn transgenic mouse model.
Identifiers
- SMILES
-
O=C(C1=CN=C(N2CCN(C)CC2)S1)N[C@@H](CC3=CNC4=C3C=CC=C4)CCCC - InChIKey
-
GDFWCSZNQVAQGR-GOSISDBHSA-N
Specifications
- MW (average)
- 425.5900
- Formula
- C23H31N5OS
- CAS No.
- 1802518-92-8
- Physical state
- Solid
- Color
- Off-white to light yellow
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- Powder 4°C, stored under nitrogen; In solvent -20℃ 1 month;
Solubility
Soluble in DMSO 100 mg/mL