STING antagonist 1 free base

STING antagonist-1 is an antagonist of STING.

For research use only. Not for human or veterinary use.

Target STING

Research area Inflammation/Immunology

Purity >98% Stock Inquire

Data Sheet SDS COA

STING antagonist 1 structure

CAS No.: 3036981-21-9

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
25 mg	USD 600.00	BP-02064-25mg	In stock	Get quote
50 mg	USD 920.00	BP-02064-50mg	In stock	Get quote
100 mg	USD 1,320.00	BP-02064-100mg	In stock	Get quote
250 mg	USD 1,820.00	BP-02064-250mg	In stock	Get quote
500 mg	USD 2,420.00	BP-02064-500mg	In stock	Get quote
1 g	Inquire	BP-02064-1g	In stock	Inquire

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Description

STING antagonist-1 is an antagonist of STING with an IC50 of 3.8 nM. STING antagonist-1 can be used in the research of autoimmune diseases, inflammatory diseases, and others.

Biological activity

In Vitro STING antagonist-1 (Compound 107) has IC50 values of 3.8 nM (HTRF) and 31 nM (HWBA) for STING.

Identifiers

SMILES: CN1C(=C(N=C1C=2C(CC)=NC=3C(C2)=CN(C)N3)C=4C=5C(=NN(C[C@H](F)C6=CC=CC=C6)C5)C=CC4)C7CC7
InChIKey: FAPBKTWPKZYLPU-VWLOTQADSA-N

Specifications

MW (average): 519.6152
Formula: C₃₁H₃₀FN₇
CAS No.: 3036981-21-9
Physical state: Solid
Color: White to off-white
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20℃ 3 years; 4℃, 2 years; In solvent -20℃ 1 month;

Solubility

Soluble in DMSO : 125 mg/mL

Documents

References

[1]. Hoffmann M, et al., Heterocyclic compounds as sting antagonists. WO2024089155A1.

Same target

Search STING

Same research area

Search Inflammation/Immunology