STING agonist-20 free base

STING agonist-20 is a potent STING agonist.

For research use only. Not for human or veterinary use.

Target STING

Research area Inflammation/Immunology Cancer

Purity >98% Stock Inquire

Data Sheet SDS COA

STING agonist-20 structure

CAS No.: 2591300-72-8

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
10 mg	USD 520.00	BP-02032-10mg	In stock	Get quote
25 mg	USD 880.00	BP-02032-25mg	In stock	Get quote
50 mg	USD 1,360.00	BP-02032-50mg	In stock	Get quote
100 mg	USD 1,960.00	BP-02032-100mg	In stock	Get quote
250 mg	USD 2,960.00	BP-02032-250mg	In stock	Get quote
500 mg	Inquire	BP-02032-500mg	In stock	Inquire

Need another size or custom synthesis? Request a quote.

Description

STING agonist-20 (compound 95) is a potent STING agonist. STING agonist-20 can be used as a vaccine adjuvant in the study of cancer and other inflammatory, immune diseases .

Biological activity

STING agonist-20 activates the STING signaling pathway in cell THP-1 with EC50 of 30-100 nM

Identifiers

SMILES: O=C(NC1=NC2=CC(C(N)=O)=CN=C2N1C/C=C/CN3C4=C(C=C(C=C4N=C3NC(C5=C(CC)N=C(C)O5)=O)C(N)=O)OCCCO)C6=C(CC)N=C(C)O6
InChIKey: BSDFGBNCRMMRDC-BQYQJAHWSA-N

Specifications

MW (average): 753.7638
Formula: C₃₆H₃₉N₁₁O₈
CAS No.: 2591300-72-8
Physical state: Solid
Color: White to light yellow
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month

Solubility

Soluble in DMSO : 80 mg/mL

Documents

References

[1]. Jeremy R. DUVALL, et al. Sting agonist compounds and methods of use. US20210032269.

Same target

Search STING

Same research area

Search Inflammation/Immunology