EZH2-IN-15 free base · Synonyms: SHR2554

EZH2-IN-15 is a EZH2 inhibitor.

For research use only. Not for human or veterinary use.

Target Histone Methyltransferase

Research area Cancer

Purity >98% Stock Inquire

Data Sheet SDS COA

EZH2-IN-15 structure

CAS No.: 2098545-98-1

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
100 mg	USD 685.00	BP-02254-100mg	In stock	Get quote
250 mg	USD 1,550.00	BP-02254-250mg	In stock	Get quote
1 g	Inquire	BP-02254-1g	In stock	Inquire
2 g	Inquire	BP-02254-2g	In stock	Inquire
5 g	Inquire	BP-02254-5g	In stock	Inquire

Need another size or custom synthesis? Request a quote.

Description

EZH2-IN-15 (SHR2554) is a EZH2 inhibitor. EZH2-IN-15 has anti-tumor activity, and can be used for research of H3K27me3-dependent tumors.

Biological activity

EZH2-IN-15 (SHR2554) is a EZH2 inhibitor.

Identifiers

SMILES: O=C1NC(C)=CC(C)=C1CNC(C2=C3C=C(CN4CCCCC4)OC3=CC(N(C5CCOCC5)CC)=C2CC)=O
InChIKey: YLZVNQZYAYVUCW-UHFFFAOYSA-N

Specifications

MW (average): 548.7162
Formula: C₃₂H₄₄N₄O₄
CAS No.: 2098545-98-1
Physical state: Solid
Color: Off-white to yellow
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month

Solubility

Soluble in DMSO

In vitro: DMSO : 125 mg/mL

Documents

References

[1]. Dale B, et al. Targeting Triple-Negative Breast Cancer by a Novel Proteolysis Targeting Chimera Degrader of Enhancer of Zeste Homolog 2. ACS Pharmacol Transl Sci. 2022 Jun 24;5(7):491-507.

Same target

Search Histone Methyltransferase

Same research area

Search Cancer