Olinciguat free base · Synonyms: IW-1701
Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator with concentration-dependent stimulation of sGC in purified rat and human enzyme…
For research use only. Not for human or veterinary use.
Target
Guanylate Cyclase
Research area
Cardiovascular Disease
Purity >98%
Stock Inquire
Olinciguat structure
CAS No.: 1628732-62-6
Pack sizes & pricing
| Size | Price | SKU | Stock | |
|---|---|---|---|---|
| 10 mg | USD 450.00 | BP-01912-10mg | In stock | Get quote |
| 25 mg | USD 750.00 | BP-01912-25mg | In stock | Get quote |
| 50 mg | USD 1,150.00 | BP-01912-50mg | In stock | Get quote |
| 100 mg | USD 1,650.00 | BP-01912-100mg | In stock | Get quote |
| 250 mg | USD 2,350.00 | BP-01912-250mg | In stock | Get quote |
| 500 mg | Inquire | BP-01912-500mg | In stock | Inquire |
| 1 g | Inquire | BP-01912-1g | Inquire | Inquire |
Need another size or custom synthesis? Request a quote.
Description
Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator with concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole cell assay.
Identifiers
- SMILES
-
FC1=C(C=CC=C1)CN2C(C3=NOC=C3)=CC(C4=NC=C(F)C(NC[C@](C(N)=O)(O)C(F)(F)F)=N4)=N2 - InChIKey
-
YWQFJNWMWZMXRW-HXUWFJFHSA-N
Specifications
- MW (average)
- 509.3889
- Formula
- C21H16F5N7O3
- CAS No.
- 1628732-62-6
- Physical state
- Solid
- Color
- white to light yellow
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Solubility
Soluble in DMSO : 125 mg/mL
Documents
References
[1]. Buys ES, et al. Discovery and development of next generation sGC stimulators with diverse multidimensional pharmacology and broad therapeutic potential. Nitric Oxide. 2018 Aug 1;78:72-80.