DCC-3014 free base · Synonyms: Vimseltinib

DCC-3014 is a c-FMS and c-Kit dual inhibitor.

For research use only. Not for human or veterinary use.

Target c-Fms c-Kit

Research area Cancer

Purity >98% Stock Inquire

Data Sheet SDS COA

DCC-3014 structure

CAS No.: 1628606-05-2

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
250 mg	USD 530.00	BP-01910-250mg	In stock	Get quote
500 mg	USD 850.00	BP-01910-500mg	In stock	Get quote
1 g	USD 1,350.00	BP-01910-1g	In stock	Get quote
2 g	Inquire	BP-01910-2g	Inquire	Inquire
5 g	Inquire	BP-01910-5g	Inquire	Inquire

Need another size or custom synthesis? Request a quote.

Description

DCC-3014 is a c-FMS (CSF-IR) and c-Kit dual inhibitor with IC50s: <0.01 μM and 0.1-1 μM. DCC-3014 has anti-cancer and anti-proliferative activities.

Biological activity

In Vitro Vimseltinib is a c-FMS (CSF-IR) and c-Kit dual inhibitor with anti-cancer and anti-proliferative activities.

Identifiers

SMILES: O=C1N(C)C(NC(C)C)=NC=C1C2=NC(C)=C(OC3=CC(C4=CN(C)N=C4)=NC=C3)C=C2
InChIKey: TVGAHWWPABTBCX-UHFFFAOYSA-N

Specifications

MW (average): 431.4903
Formula: C₂₃H₂₅N₇O₂
CAS No.: 1628606-05-2
Physical state: Solid
Color: Off-white to light yellow
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20℃ 2 years; In solvent -20℃ 1 month;

Solubility

Soluble in DMSO

Documents

References

[1]. Yumi Ahn, et al. 2-aminopyrimidin-6-ones and analogs exhibiting anti-cancer and anti-proliferative activities. WO2014145025A2.

[2]. Kisielewska K, et al. An evaluation of vimseltinib for treatment of tenosynovial giant cell tumors. Expert Rev Anticancer Ther. 2025 Apr;25(4):327-335.

Same target

Search c-Fms

Same research area

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