Lp(a)-IN-5 free base · Synonyms: HRS-5346

Lp-IN-5 is an orally active lipoprotein) inhibitor.

For research use only. Not for human or veterinary use.

Target Apolipoprotein

Research area Cardiovascular Disease

Purity >98% Stock Inquire

Data Sheet SDS COA

Lp(a)-IN-5 structure

CAS No.: 2924841-79-0

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
100 mg	USD 800.00	BP-00840-100mg	In stock	Get quote
250 mg	USD 1,250.00	BP-00840-250mg	In stock	Get quote
500 mg	USD 1,650.00	BP-00840-500mg	In stock	Get quote
1 g	USD 2,550.00	BP-00840-1g	In stock	Get quote
2 g	Inquire	BP-00840-2g	In stock	Inquire
5 g	Inquire	BP-00840-5g	In stock	Inquire

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Description

Lp(a)-IN-5 (Compound A) is an orally active lipoprotein (a) (Lp(a)) inhibitor. Lp(a)-IN-5 inhibits the assembly of Apo(a) and ApoB proteins with an IC50 value of 0.41 nM. Lp(a)-IN-5 is promising for research of diseases related to elevated plasma Lp(a) levels, such as cardiovascular diseases.

Biological activity

In Vitro Lp(a)-IN-5 inhibits the assembly of Apo(a) and ApoB proteins with an IC50 value of 0.41 nM.

Identifiers

SMILES: C([C@H](C(O)=O)[C@]1(CCNC1)[H])C2=CC(CN(CC3=CC(C[C@H](C(O)=O)[C@]4(CCNC4)[H])=CC=C3)CCOC5=CC(C[C@H](C(O)=O)[C@]6(CCNC6)[H])=CC=C5)=CC=C2
InChIKey: CIYXAQSCBUSSGM-FOZRYHJYSA-N

Specifications

MW (average): 740.9273
Formula: C₄₃H₅₆N₄O₇
CAS No.: 2924841-79-0
Physical state: Solid
Color: yellow
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20℃ 3 years, protect from light; In solvent -20℃ 1 month;

Solubility

soluble in DMSO

Documents

References

[1]. Yao JQ, et al. Crystal form of lipoprotein compound and preparation method therefor. WO2024230805A1. 2024-11-14.

Same research area

Search Cardiovascular Disease