TAK-653 free base · Synonyms: TAK 653 · TAK653
TAK-653 is an AMPA receptor potentiator with minimal agonistic activity.
For research use only. Not for human or veterinary use.
TAK-653 structure
CAS No.: 1358751-06-0
Pack sizes & pricing
| Size | Price | SKU | Stock | |
|---|---|---|---|---|
| 250 mg | USD 550.00 | BP-01876-250mg | In stock | Get quote |
| 500 mg | USD 750.00 | BP-01876-500mg | In stock | Get quote |
| 1 g | USD 1,350.00 | BP-01876-1g | In stock | Get quote |
| 5 g | Inquire | BP-01876-5g | Inquire | Inquire |
Need another size or custom synthesis? Request a quote.
Description
TAK-653 is an AMPA receptor potentiator with minimal agonistic activity.
Biological activity
TAK-653, an AMPA receptor potentiator with minimal agonistic activity, produces an antidepressant-like effect with a favorable safety profile in rats. In Vivo Osavampator (0.03-0.3 mg/kg, p.o., single dose) enhances visual learning and memory in normal rats. Osavampator (0.3 mg/kg, p.o., single dose) enhances sustained attention in the poor performing rats. Osavampator (0.06 mg/kg, p.o., single dose) improves working memory in monkeys. Osavampator (1 mg/kg, p.o., single dose) produces antidepressant-like effects in the rat RSBM (reduction of submissive behavior model).
Identifiers
- SMILES
-
O=S1(N=C2C(C3=CC=C(C=C3)OC4CCCCC4)=NC(C)=CN2CC1)=O - InChIKey
-
PXJBHEHFVQVDDS-UHFFFAOYSA-N
Specifications
- MW (average)
- 373.4690
- Formula
- C19H23N3O3S
- CAS No.
- 1358751-06-0
- Physical state
- Solid
- Color
- White to yellow
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- Powder 4°C, sealed storage, away from moisture and light; In solvent -20℃ 1 month;
Solubility
Soluble in DMSO ≥ 12.5 mg/mL