AZD-7594 free base · Synonyms: Velsecorat
AZD7594 is a potent selective nonsteroidal glucocorticoid receptor modulator.
For research use only. Not for human or veterinary use.
AZD-7594 structure
CAS No.: 1196509-60-0
Pack sizes & pricing
| Size | Price | SKU | Stock | |
|---|---|---|---|---|
| 50 mg | USD 395.00 | BP-01848-50mg | In stock | Get quote |
| 100 mg | USD 608.00 | BP-01848-100mg | In stock | Get quote |
| 250 mg | USD 920.00 | BP-01848-250mg | In stock | Get quote |
| 500 mg | USD 1,380.00 | BP-01848-500mg | In stock | Get quote |
| 1 g | Inquire | BP-01848-1g | In stock | Inquire |
Need another size or custom synthesis? Request a quote.
Description
AZD7594 is a potent selective nonsteroidal glucocorticoid receptor modulator, with an IC50 of 0.9 nM.
Biological activity
In Vitro AZD7594 is a potent selective nonsteroidal glucocorticoid receptor modulator, with an IC50 of 0.9 nM. AZD7594 shows no effect on progesterone receptor, mineralocorticoid receptor, Androgen receptor, ERα or ERβ (IC50, > 10 μM). In Vivo AZD7594 has anti-inflammatory activity, and efficiently inhibits rat lung edema.
Identifiers
- SMILES
-
C[C@H](NC(=O)C(C)(F)F)[C@H](OC1=CC2=C(C=C1)N(N=C2)C1=CC(=CC=C1)C(=O)N[C@@H]1CCOC1)C1=CC=C2OCCOC2=C1 - InChIKey
-
ZZWJKLGCDHYVMB-BWGXUDETSA-N
Specifications
- MW (average)
- 606.6165
- Formula
- C32H32F2N4O6
- CAS No.
- 1196509-60-0
- Physical state
- Solid
- Color
- white to off-white
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- Powder -20℃ 3 years; In solvent -20℃ 1 month;
Solubility
Soluble in DMSO