BiochemProbe — Life Science Research Reagents

CDK7 ligand 2 free base

CDK7 ligand 2 is a CDK7 ligand.

For research use only. Not for human or veterinary use.

Purity >98% Stock Inquire

CDK7 ligand 2 structure

CAS No.: 2603381-71-9

Download structure (.mol)

Pack sizes & pricing

Size Price SKU Stock
100 mg USD 598.00 BP-02387-100mg In stock Get quote
250 mg USD 1,100.00 BP-02387-250mg In stock Get quote
500 mg USD 1,900.00 BP-02387-500mg In stock Get quote
1 g Inquire BP-02387-1g In stock Inquire

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Description

CDK7 ligand 2 (Compound A6) is a CDK7 ligand. CDK7 ligand 2 can be used in the synthesis of PROTACs.

Identifiers

SMILES
N(C(=O)C1=CC=C(C(O)=O)C=C1)C=2C3=C(C(C)(C)N(C(N[C@H](CN(C)C)C4=CC=CC=C4)=O)C3)NN2
InChIKey
FWPHDQJJYVZOKA-HXUWFJFHSA-N

Specifications

MW (average)
490.5542
Formula
C26H30N6O4
CAS No.
2603381-71-9
Physical state
Solid
Color
White to off-white
Shipping
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage
Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month.

Solubility

Soluble in DMSO

In vitro
DMSO : 50 mg/mL

References

[1]. Wenzhi Ji, et al. Discovery of Bivalent Small Molecule Degraders of Cyclin-dependent Kinase 7 (CDK7). European Journal of Medicinal Chemistry (2024): 116613.

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