TC-FPR 43 free base
FPR Agonist 43 is a dual formyl peptide receptor 1 and formyl peptide receptor 2/ALX agonist.
For research use only. Not for human or veterinary use.
TC-FPR 43 structure
CAS No.: 903895-98-7
Pack sizes & pricing
Description
FPR Agonist 43 (compound 43) is a dual formyl peptide receptor 1 (FPR1) and formyl peptide receptor 2 (FPR2)/ALX agonist.
Biological activity
In Vitro FPR Agonist 43 (10-5-107 nM) is actively potent in the cAMP assay in FPR2/ALX over-expressing CHO cells. FPR Agonist 43 is also active in the GTPγ binding assay (IC50=207±51 nM). FPR1 is the preferred receptor for FPR Agonist 43 in in both human neutrophils and possibly also in mouse cells.
Identifiers
- SMILES
-
O=C(NC1=C(C(C)C)N(C)N(C2=CC=CC=C2)C1=O)NC3=CC=C(Cl)C=C3 - InChIKey
-
PAEBEUZTAPIOIO-UHFFFAOYSA-N
Specifications
- MW (average)
- 384.8590
- Formula
- C20H21ClN4O2
- CAS No.
- 903895-98-7
- Physical state
- Solid
- Color
- white to light yellow
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- Powder 4℃, sealed storage, away from moisture; In solvent -20℃ 1 month;
Solubility
Soluble in DMSO : 37.5 mg/mL H2O : < 0.1 mg/mL
- In vitro
- Soluble in DMSO : 37.5 mg/mL H2O : < 0.1 mg/mL