Ochnaflavone free base

Ochnaflavone is an inhibitor of IIA-type secretory phospholipase A2.

For research use only. Not for human or veterinary use.

Target Phospholipase

Research area Inflammation/Immunology

Purity >98% Stock Inquire

Data Sheet SDS COA

Ochnaflavone structure

CAS No.: 50276-96-5

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
1 mg	USD 580.00	BP-02207-1mg	In stock	Get quote
5 mg	USD 1,480.00	BP-02207-5mg	In stock	Get quote
10 mg	USD 2,360.00	BP-02207-10mg	In stock	Get quote
25 mg	USD 4,700.00	BP-02207-25mg	In stock	Get quote
50 mg	Inquire	BP-02207-50mg	In stock	Inquire

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Description

Ochnaflavone is an inhibitor of IIA-type secretory phospholipase A2 (sPLA2-IIA) with an IC50 of 3.45 µM. Ochnaflavone exhibits significant anti-inflammatory and liver-protective effects, capable of inhibiting the degradation of phosphatidylethanolamine (PE) and lipid peroxidation induced by carbon tetrachloride (CCl4) in rat liver, with an IC50 of 7.16 µM for lipid peroxidation. Ochnaflavone can be used in research on liver damage and inflammatory diseases[1].

Identifiers

SMILES: O=C1C=C(C2=CC=C(OC3=CC(C4=CC(C5=C(O)C=C(O)C=C5O4)=O)=CC=C3O)C=C2)OC6=CC(O)=CC(O)=C16
InChIKey: NNPGECDACGBKDH-UHFFFAOYSA-N

Specifications

MW (average): 538.4579
Formula: C₃₀H₁₈O₁₀
CAS No.: 50276-96-5
Physical state: Solid
Color: Yellow to brown
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder 4°C, protect from light; In solvent -20°C, 1 month;

Solubility

soluble in DMSO

Documents

References

[1]. Moon TC, et al. Ochnaflavone, naturally occurring biflavonoid, inhibits phospholipase A2 dependent phosphatidylethanolamine degradation in a CCl4-induced rat liver microsome. Biol Pharm Bull. 2006 Dec;29(12):2359-61.

Same research area

Search Inflammation/Immunology