BAY 1161909 free base · Synonyms: Empesertib

Empesertib is a potent Mps1 inhibitor.

For research use only. Not for human or veterinary use.

Target Mps1

Research area Cancer

Purity >98% Stock Inquire

Data Sheet SDS COA

BAY 1161909 structure

CAS No.: 1443763-60-7

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
250 mg	USD 495.00	BP-01891-250mg	In stock	Get quote
500 mg	USD 795.00	BP-01891-500mg	In stock	Get quote
1 g	USD 1,295.00	BP-01891-1g	In stock	Get quote
2 g	Inquire	BP-01891-2g	Inquire	Inquire

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Description

Empesertib (BAY 1161909) is a potent Mps1 inhibitor, with an IC50 of < 1 nM.

Biological activity

In Vitro BAY 1161909 is a potent Mps1 inhibitor, with an IC50 of < 1 nM. BAY 1161909 also shows anti-tumor effect, suppressing the proliferation of Hela cells, with an IC50 of < 400 nM.

Identifiers

SMILES: FC1=CC=C([C@@H](C)C(NC2=CC=C(C3=CN4N=C(NC5=CC=C(S(C)(=O)=O)C=C5OC)N=C4C=C3)C=C2)=O)C=C1
InChIKey: NRJKIOCCERLIDG-GOSISDBHSA-N

Specifications

MW (average): 559.6110
Formula: C₂₉H₂₆FN₅O₄S
CAS No.: 1443763-60-7
Physical state: Solid
Color: White to pink
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20℃ 2 years; In solvent -20℃ 1 month;

Solubility

Soluble in DMSO/water

Documents

References

[1]. SCHULZE, Volker, et al. PRODRUG DERIVATIVES OF SUBSTITUTED TRIAZOLOPYRIDINES. WO2014198647A2

Same research area

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