BiochemProbe — Life Science Research Reagents

Bromperidol free base · Synonyms: R-11333

Bromperidol (R-11333) possesses antipsychotic activity, with a high affinity for central dopamine receptors D2.

For research use only. Not for human or veterinary use.

Purity >98% Stock Inquire

Bromperidol structure

CAS No.: 10457-90-6

Download structure (.mol)

Pack sizes & pricing

Size Price SKU Stock
250 mg USD 360.00 BP-02181-250mg In stock Get quote
500 mg USD 570.00 BP-02181-500mg In stock Get quote
1 g USD 920.00 BP-02181-1g In stock Get quote
2 g USD 1,450.00 BP-02181-2g In stock Get quote
3 g USD 1,750.00 BP-02181-3g In stock Get quote
5 g USD 2,300.00 BP-02181-5g In stock Get quote

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Description

Bromperidol (R-11333) possesses antipsychotic activity, with a high affinity for central dopamine receptors D2. Bromperidol can kill Mycobacteria in a synergistic manner with Spectinomycin .

Biological activity

In Vivo Bromperidol antagonises stereotyped behaviour and agitation induced by apomorphine or amphetamine, and inhibits conditioned reactions and learned intracranial self-stimulation in rats. Bromperidol antagonises apomorphine-induced emesis and inhibits the conditioned avoidance response in dogs.

Identifiers

SMILES
O=C(C1=CC=C(F)C=C1)CCCN2CCC(O)(C3=CC=C(Br)C=C3)CC2
InChIKey
RKLNONIVDFXQRX-UHFFFAOYSA-N

Specifications

MW (average)
420.3150
Formula
C21H23BrFNO2
CAS No.
10457-90-6
Physical state
Solid
Color
White to yellow
Shipping
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage
Powder -20℃ 3 years; 4℃ 2 years; In solvent -20℃ 1 month;

Solubility

soluble in DMSO

References

[1]. Benfield P, et al. Bromperidol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in psychoses. Drugs. 1988 Jun;35(6):670-84.
[2]. Ramón-García S, et al. Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen. Antimicrob Agents Chemother. 2011 Aug;55(8):3861-9.

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