JNJ-37822681 free base · Synonyms: CPDA602231

JNJ-37822681 is a fast dissociating D2 antagonist.

For research use only. Not for human or veterinary use.

Target Dopamine Receptor

Research area Others

Purity >98% Stock Inquire

Data Sheet SDS COA

JNJ-37822681 structure

CAS No.: 935776-74-2

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
500 mg	USD 450.00	BP-02109-500mg	In stock	Get quote
1 g	USD 798.00	BP-02109-1g	In stock	Get quote
2 g	USD 1,450.00	BP-02109-2g	In stock	Get quote
5 g	Inquire	BP-02109-5g	In stock	Inquire
10 g	Inquire	BP-02109-10g	In stock	Inquire

Need another size or custom synthesis? Request a quote.

Description

JNJ-37822681 is a fast dissociating D2 antagonist with activity in inhibiting schizophrenia. JNJ-37822681 has high specificity for D2 receptors and is effective in animal models, inducing increased levels of extracellular serotonin, dopamine, and norepinephrine in the rat cerebral cortex, and exhibiting antidepressant activity in the mouse tail suspension test, while having a good brain distribution and lower prolactin release.

Identifiers

SMILES: FC1=CC=C(CN2CCC(CC2)NC3=NN=C(C(F)(F)F)C=C3)C=C1F
InChIKey: UVUYWJWYRLJHEN-UHFFFAOYSA-N

Specifications

MW (average): 372.3357
Formula: C₁₇H₁₇F₅N₄
CAS No.: 935776-74-2
Physical state: Solid
Color: White to off-white
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Solubility

Soluble in DMSO

Documents

References

[1]. Pharmacology of JNJ-37822681, a specific and fast-dissociating D2 antagonist for the treatment of schizophrenia

Same target

Search Dopamine Receptor

Same research area

Search Others