Phortress free base

Phortress is a high affinity AhR ligand.

For research use only. Not for human or veterinary use.

Target Cytochrome P450

Research area Cancer

Purity >98% Stock Inquire

Data Sheet SDS COA

Phortress structure

CAS No.: 328087-38-3

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
50 mg	USD 498.00	BP-02448-50mg	In stock	Get quote
100 mg	USD 796.00	BP-02448-100mg	In stock	Get quote
250 mg	USD 1,594.00	BP-02448-250mg	In stock	Get quote
500 mg	USD 2,550.00	BP-02448-500mg	In stock	Get quote
1 g	USD 4,080.00	BP-02448-1g	In stock	Get quote
2 g	Inquire	BP-02448-2g	In stock	Inquire

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Description

Phortress is a high affinity AhR ligand that elicits antitumor activity by inducing transcription of CYP1A1 .

Identifiers

SMILES: O=C(NC1=CC=C(C2=NC3=CC(F)=CC=C3S2)C=C1C)[C@@H](N)CCCCN.[H]Cl.[H]Cl
InChIKey: QZSMNTOCJVVFEU-CKUXDGONSA-N

Specifications

MW (average): 459.4080
Formula: C₂₀H₂₅Cl₂FN₄OS
CAS No.: 328087-38-3
Physical state: Solid
Color: Light yellow to yellow
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20°C, sealed storage, away from moisture; In solvent -20℃ 1 month;

Solubility

Soluble in DMSO

Documents

References

[1].Bradshaw TD, et al. In vitro evaluation of amino acid prodrugs of novel antitumour 2-(4-amino-3-methylphenyl)benzothiazoles. Br J Cancer. 2002 Apr 22;86(8):1348-54.

[2].Bradshaw TD, Westwell AD. The development of the antitumour benzothiazole prodrug, Phortress, as a clinical candidate. Curr Med Chem. 2004 Apr;11(8):1009-21.

Same target

Search Cytochrome P450

Same research area

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