ABI-H0731 free base · Synonyms: Vebicorvir

ABI-H0731 is a first-generation hepatitis B virus core protein inhibitor.

For research use only. Not for human or veterinary use.

Target HBV

Research area Infection Inflammation/Immunology

Purity >98% Stock Inquire

Data Sheet SDS COA

ABI-H0731 structure

CAS No.: 2090064-66-5

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
250 mg	USD 850.00	BP-02368-250mg	In stock	Get quote
500 mg	USD 1,200.00	BP-02368-500mg	In stock	Get quote
1 g	USD 1,900.00	BP-02368-1g	In stock	Get quote
2 g	USD 2,980.00	BP-02368-2g	In stock	Get quote
5 g	Inquire	BP-02368-5g	In stock	Inquire

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Description

ABI-H0731 (Vebicorvir) is a first-generation hepatitis B virus (HBV) core protein inhibitor, has demonstrated effective antiviral activity.

Biological activity

Gilmelisib is an antineoplastic. Gilmelisib is a PI3K inhibitor (IC50 <1 nM for PI3K p110α).

Identifiers

SMILES: O=C(C1=CC=C(C(NC(C2=CC=CC=C23)=O)=C1)S3(=O)=O)NCC4=CN=C(C(F)(F)F)S4
InChIKey: LBJVBJYMZKEREY-UHFFFAOYSA-N

Specifications

MW (average): 467.4410
Formula: C₁₉H₁₂F₃N₃O₄S₂
CAS No.: 2090064-66-5
Physical state: Solid
Color: White to off-white
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20℃ 2 years; In solvent -20℃ 1 month;

Solubility

Soluble in DMSO

In vitro: DMSO : 100 mg/mL

Documents

References

[1]. Qi Huang, et al. Preclinical Profile and Characterization of the Hepatitis B Virus Core Protein Inhibitor ABI-H0731. Antimicrob Agents Chemother. 2020 Oct 20;64(11):e01463-20.

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