Selgantolimod free base · Synonyms: GS-9688

Selgantolimod is an orally active, potent and selective toll-like receptor 8 agonist.

For research use only. Not for human or veterinary use.

Target Toll-like Receptor (TLR) HBV

Research area Infection

Purity >98% Stock Inquire

Data Sheet SDS COA

Selgantolimod structure

CAS No.: 2004677-13-6

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
25 mg	USD 598.00	BP-02354-25mg	In stock	Get quote
50 mg	USD 898.00	BP-02354-50mg	In stock	Get quote
100 mg	USD 1,500.00	BP-02354-100mg	In stock	Get quote
250 mg	USD 2,700.00	BP-02354-250mg	In stock	Get quote
500 mg	Inquire	BP-02354-500mg	In stock	Inquire
1 g	Inquire	BP-02354-1g	In stock	Inquire

Need another size or custom synthesis? Request a quote.

Description

Selgantolimod (GS-9688) is an orally active, potent and selective toll-like receptor 8 (TLR8) agonist for the treatment of hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infection.

Biological activity

Selgantolimod (GS-9688) is an orally active, potent and selective Toll-like receptor 8 (TLR8) agonist for the study of hepatitis B virus (HBV) and HIV infection.

Identifiers

SMILES: C[C@@](CCCC)(CO)NC1=NC(N)=NC2=C1N=CC(F)=C2
InChIKey: HTCJUBZBSJQWBW-CQSZACIVSA-N

Specifications

MW (average): 293.3399
Formula: C₁₄H₂₀FN₅O
CAS No.: 2004677-13-6
Physical state: Solid
Color: Light yellow to yellow
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20℃ 2 years; In solvent -20℃ 1 month;

Solubility

Soluble in DMSO

Documents

References

[1]. Jules Levin. Efficacy and Safety of Oral TLR8 Agonist Selgantolimod in Virally Suppressed Adult Patients With Chronic Hepatitis B: a Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study. 2019 Nov 8-12.

[2]. Benjamin Ryan. Selgantolimod Shows Promise as Treatment for Hepatitis B. November 18, 2019.

[3]. Romas Geleziunas, et al. Modulators of toll-like receptors for the treatment of hiv. US20170071944A1.

Same target

Search Toll-like Receptor (TLR)

Same research area

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