(R)-SARM1-IN-5 free base · Synonyms: (R)-3-((6-fluoropyridin-3-yl)methyl)-1-(3-(pyridin-4-yl)-1H-1,2,4-triazol-5-yl)piperidin-2-one
(R)-SARM1-IN-5 is the (R)-enantiomer of SARM1-IN-5 .
For research use only. Not for human or veterinary use.
Target
Toll-like Receptor (TLR)
Purity >98%
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(R)-SARM1-IN-5 structure
CAS No.: 2762081-31-0
Pack sizes & pricing
Description
(R)-SARM1-IN-5 is the (R)-enantiomer of SARM1-IN-5 . SARM1-IN-5 (compound 1-23-a) is a SARM1 inhibitor. SARM1-IN-5 can be used in the study of axonal degeneration related diseases such as Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS)[1].
Identifiers
- SMILES
-
O=C1N(CCC[C@@H]1CC=2C=CC(F)=NC2)C=3NC(=NN3)C=4C=CN=CC4 - InChIKey
-
BYBKCHFWMZWSCS-CQSZACIVSA-N
Specifications
- MW (average)
- 352.3656
- Formula
- C18H17FN6O
- CAS No.
- 2762081-31-0
- Physical state
- Solid
- Color
- White to off-white
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- Powder -20℃ 3 years; In solvent -20℃ 1 month;
Solubility
Soluble in DMSO, >50 mg/mL
Documents
References
[1]. Jennifer Anne Mcmahon, et al. (s)-3-((6-fluoropyridin-3-yl)methyl)-1-(5-(pyridin-4-yl)-4h-1,2,4-triazol-3-yl)piperidin-2-one benzenesulfonate. WO2025049184. 2025-03-06.