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Lp(a)-IN-5 hydrochloride salt form · hydrochloride · Parent Lp(a)-IN-5 hydrochloride · Synonyms: Lp(a)-IN-5 Tetrahydrochloride

Lp-IN-5 hydrochloride is an orally active lipoprotein) inhibitor.

For research use only. Not for human or veterinary use.

Target Apolipoprotein
Research area Cardiovascular Disease
Purity >98% Stock Inquire
Data Sheet SDS COA

Lp(a)-IN-5 hydrochloride structure

CAS No.: 2924841-80-3

Download structure (.mol)

Pack sizes & pricing

Size Price SKU Stock
100 mg USD 800.00 BP-02282A-100mg In stock Get quote
250 mg USD 1,250.00 BP-02282A-250mg In stock Get quote
500 mg USD 1,650.00 BP-02282A-500mg In stock Get quote
1 g USD 2,550.00 BP-02282A-1g In stock Get quote
2 g Inquire BP-02282A-2g In stock Inquire
5 g Inquire BP-02282A-5g In stock Inquire

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Description

Lp(a)-IN-5 hydrochloride (Compound A) is an orally active lipoprotein (a) (Lp(a)) inhibitor. Lp(a)-IN-5 inhibits the assembly of Apo(a) and ApoB proteins with an IC50 value of 0.41 nM. Lp(a)-IN-5 is promising for research of diseases related to elevated plasma Lp(a) levels, such as cardiovascular diseases.

Biological activity

In Vitro Lp(a)-IN-5 hydrochloride inhibits the assembly of Apo(a) and ApoB proteins with an IC50 value of 0.41 nM

Identifiers

SMILES
O=C(O)[C@H]([C@H]1CCNC1)CC2=CC=CC(CN(CC3=CC(C[C@H](C(O)=O)[C@H]4CCNC4)=CC=C3)CCOC5=CC(C[C@H](C(O)=O)[C@H]6CCNC6)=CC=C5)=C2.Cl.Cl.Cl.Cl
InChIKey
MVBZVPHXHRIJCX-FDQJPOKASA-N

Specifications

MW (average)
886.7710
Formula
C43H60Cl4N4O7
CAS No.
2924841-80-3
Physical state
Solid
Color
White to off-white
Shipping
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage
Powder -20℃ 3 years, protect from light; In solvent -20℃ 1 month;

Solubility

soluble in H2O

In vitro
H2O : 50 mg/mL

Documents

References

[1]. Yao JQ, et al. Crystal form of lipoprotein compound and preparation method therefor. WO2024230805A1. 2024-11-14.

Same target

Search Apolipoprotein

Same research area

Search Cardiovascular Disease