Inaxaplin free base · Synonyms: VX-147

Inaxaplin is an apolipoprotein L1 function inhibitor.

For research use only. Not for human or veterinary use.

Target Apolipoprotein

Research area Others

Purity >98% Stock Inquire

Data Sheet SDS COA

Inaxaplin structure

CAS No.: 2446816-88-0

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
100 mg	USD 520.00	BP-02020-100mg	In stock	Get quote
250 mg	USD 880.00	BP-02020-250mg	In stock	Get quote
500 mg	USD 1,340.00	BP-02020-500mg	In stock	Get quote
1 g	USD 1,920.00	BP-02020-1g	In stock	Get quote
5 g	Inquire	BP-02020-5g	In stock	Inquire

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Description

Inaxaplin is an apolipoprotein L1 (APOL1) function inhibitor (WO2020131807A1, compound 2). Inaxaplin can be used for the research of kidney disease.

Biological activity

In Vitro Inaxaplin is an apolipoprotein L1 function inhibitor.

Identifiers

SMILES: O=C(N[C@@H]1C(NC[C@H]1O)=O)CCC2=C(C3=CC=C(F)C=C3)NC4=C2C=C(F)C=C4F
InChIKey: CTXLPYZCBOVVQK-UZLBHIALSA-N

Specifications

MW (average): 417.3811
Formula: C₂₁H₁₈F₃N₃O₃
CAS No.: 2446816-88-0
Physical state: Solid
Color: White to off-white
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20℃ 2 years; In solvent -20℃ 1 month;

Solubility

Soluble in DMSO 50 mg/mL

Documents

References

[1]. WO2020131807A1

[2]. Egbuna, Ogo et al. “Inaxaplin for Proteinuric Kidney Disease in Persons with Two APOL1 Variants.” The New England journal of medicine vol. 388,11 (2023): 969-979.

Same target

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Same research area

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