CJ-13610 free base · Synonyms: CJ 13610 · CJ13610
CJ-13,610, a nonredox-type 5-LO inhibitor, dose dependently suppresses 5-LO product formation in ionophore A23187-stimulated PMNL in the absence of…
For research use only. Not for human or veterinary use.
Target
Lipoxygenase
Research area
Inflammation/Immunology
Purity >98%
Stock Inquire
CJ-13610 structure
CAS No.: 179420-17-8
Pack sizes & pricing
| Size | Price | SKU | Stock | |
|---|---|---|---|---|
| 25 mg | USD 400.00 | BP-02164-25mg | In stock | Get quote |
| 50 mg | USD 620.00 | BP-02164-50mg | In stock | Get quote |
| 100 mg | USD 990.00 | BP-02164-100mg | In stock | Get quote |
| 250 mg | USD 2,040.00 | BP-02164-250mg | In stock | Get quote |
| 500 mg | USD 3,250.00 | BP-02164-500mg | In stock | Get quote |
Need another size or custom synthesis? Request a quote.
Description
CJ-13,610, a nonredox-type 5-LO inhibitor, dose dependently suppresses 5-LO product formation in ionophore A23187-stimulated PMNL in the absence of exogenous AA with an IC50 of about 70 nM. PMNL: polymorphonuclear leukocytes; AA: arachidonic acid.
Identifiers
- SMILES
-
NC(C1(C2=CC(SC3=CC=C(N4C(C)=NC=C4)C=C3)=CC=C2)CCOCC1)=O - InChIKey
-
VPTONMHDLLMOOV-UHFFFAOYSA-N
Specifications
- MW (average)
- 393.5020
- Formula
- C22H23N3O2S
- CAS No.
- 179420-17-8
- Physical state
- Solid
- Color
- White to off-white
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- Powder -20℃ 3 years; 4℃, 2 years; In solvent -20℃ 1 month;
Solubility
Soluble in DMSO : 10 mg/mL
Documents
References
[1]. Fischer L, et al. Molecular pharmacological profile of the nonredox-type 5-lipoxygenase inhibitor CJ-13,610. Br J Pharmacol. 2004;142(5):861-868.