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CJ-13610 free base · Synonyms: CJ 13610 · CJ13610

CJ-13,610, a nonredox-type 5-LO inhibitor, dose dependently suppresses 5-LO product formation in ionophore A23187-stimulated PMNL in the absence of…

For research use only. Not for human or veterinary use.

Target Lipoxygenase
Research area Inflammation/Immunology
Purity >98% Stock Inquire

CJ-13610 structure

CAS No.: 179420-17-8

Download structure (.mol)

Pack sizes & pricing

Size Price SKU Stock
25 mg USD 400.00 BP-02164-25mg In stock Get quote
50 mg USD 620.00 BP-02164-50mg In stock Get quote
100 mg USD 990.00 BP-02164-100mg In stock Get quote
250 mg USD 2,040.00 BP-02164-250mg In stock Get quote
500 mg USD 3,250.00 BP-02164-500mg In stock Get quote

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Description

CJ-13,610, a nonredox-type 5-LO inhibitor, dose dependently suppresses 5-LO product formation in ionophore A23187-stimulated PMNL in the absence of exogenous AA with an IC50 of about 70 nM. PMNL: polymorphonuclear leukocytes; AA: arachidonic acid.

Identifiers

SMILES
NC(C1(C2=CC(SC3=CC=C(N4C(C)=NC=C4)C=C3)=CC=C2)CCOCC1)=O
InChIKey
VPTONMHDLLMOOV-UHFFFAOYSA-N

Specifications

MW (average)
393.5020
Formula
C22H23N3O2S
CAS No.
179420-17-8
Physical state
Solid
Color
White to off-white
Shipping
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage
Powder -20℃ 3 years; 4℃, 2 years; In solvent -20℃ 1 month;

Solubility

Soluble in DMSO : 10 mg/mL

References

[1]. Fischer L, et al. Molecular pharmacological profile of the nonredox-type 5-lipoxygenase inhibitor CJ-13,610. Br J Pharmacol. 2004;142(5):861-868.

Same research area

Search Inflammation/Immunology