BiochemProbe — Life Science Research Reagents

Antiviral agent 17 free base

Antiviral agent 17 is an anti-infection agent.

For research use only. Not for human or veterinary use.

Research area Infection
Purity >98% Stock Inquire

Antiviral agent 17 structure

CAS No.: 158227-81-7

Download structure (.mol)

Pack sizes & pricing

Size Price SKU Stock
250 mg USD 420.00 BP-02414-250mg In stock Get quote
500 mg USD 650.00 BP-02414-500mg In stock Get quote
1 g USD 1,050.00 BP-02414-1g In stock Get quote
2 g USD 1,680.00 BP-02414-2g In stock Get quote
3 g USD 2,015.00 BP-02414-3g In stock Get quote
5 g USD 2,686.00 BP-02414-5g In stock Get quote
10 g USD 4,298.00 BP-02414-10g In stock Get quote

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Description

Antiviral agent 17 is an anti-infection agent. Antiviral agent 17 retains its antiviral effect in a human replicon assay (EC50 = 0.015 μM). Antiviral agent 17 results in good antiviral activity against murine norovirus with an EC50 of 7 nM. . Antiviral agent 17 has the potential for the research of infectious and malignant diseases .

Biological activity

In Vitro Antiviral agent 17 (Compound 4) reduces the levels of HuNoV virus RNA with an EC50 of 0.015 µM. However, at concentrations higher than the EC50, a toxic effect was observed on the host cells.

Identifiers

SMILES
NC1=NC=NN2C1=CC=C2[C@@H]3O[C@@H]([C@H]([C@H]3O)O)CO
InChIKey
IGZFWIAREXANMY-KYXWUPHJSA-N

Specifications

MW (average)
266.2533
Formula
C11H14N4O4
CAS No.
158227-81-7
Physical state
Solid
Color
White to off-white
Shipping
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage
4°C, sealed storage, away from moisture and light

Solubility

Soluble in DMSO : 125 mg/mL

References

[1].Li Q, et al. Anti-norovirus activity of C7-modified 4-amino-pyrrolo[2,1-f][1,2,4]triazine C-nucleosides. Eur J Med Chem. 2020 Jun 1;195:112198.

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