BiochemProbe — Life Science Research Reagents

Retagliptin phosphate salt form · phosphate · Parent Retagliptin phosphate · Synonyms: SP2086 phosphate

Retagliptin phosphate is a selective, competitive and orally active dipeptidyl peptidase-4 inhibitor.

For research use only. Not for human or veterinary use.

Target Dipeptidyl Peptidase
Research area Metabolic Disease
Purity >98% Stock Inquire
Data Sheet SDS COA

Retagliptin phosphate structure

CAS No.: 1256756-88-3

Download structure (.mol)

Pack sizes & pricing

Size Price SKU Stock
100 mg USD 350.00 BP-01859A-100mg In stock Get quote
250 mg USD 650.00 BP-01859A-250mg In stock Get quote
500 mg USD 1,050.00 BP-01859A-500mg In stock Get quote
1 g USD 1,650.00 BP-01859A-1g In stock Get quote
Custom Size Bulk Inquiry

Description

Retagliptin phosphate (SP2086 phosphate) is a selective, competitive and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor. Retagliptin phosphate can be used for type 2 diabetes mellitus (T2DM) research.

Biological activity

In Retagliptin is a class of compound used for research of type 2 diabetes. Retagliptin inhibits the degradation of GLP-1, thus amplifying the incretin effect.

Identifiers

SMILES
OP(O)(O)=O.COC(=O)C1=C2CN(CCN2C(=N1)C(F)(F)F)C(=O)C[C@H](N)CC1=CC(F)=C(F)C=C1F
InChIKey
SFNHOWDAQMIJPX-HNCPQSOCSA-N

Specifications

MW (average)
562.3568
Formula
C19H21F6N4O7P
CAS No.
1256756-88-3
Physical state
Solid
Color
white to light yellow
Shipping
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage
Powder -20℃ 2 years; In solvent -20℃ 1 month;

Solubility

Soluble in DMSO

Documents

References

[1]. Hu C, et al. Pharmacokinetics of Phosphate Retagliptin Tabletin in Patients with Renal Dysfunction. Sichuan Da Xue Xue Bao Yi Xue Ban. 2018 Jan;49(1):74-80.
[2]. Avivit Cahn, et al. An update on DPP-4 inhibitors in the management of type 2 diabetes. Expert Opin Emerg Drugs. 2016 Dec;21(4):409-419.

Same target

Search Dipeptidyl Peptidase

Same research area

Search Metabolic Disease