Petrelintide free base · Synonyms: ZP8396

Petrelintide (ZP8396) is a dual amylin and calcitonin receptor agonist (DACRA) Petrelintide elicits a selective reduction in high-fat diet intake in…

For research use only. Not for human or veterinary use.

Target Amylin Receptor

Research area Metabolic Disease

Purity >98%

Data Sheet SDS COA

Petrelintide sequence

CAS No.: 2766385-23-1

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
5 mg	USD 972.00	BP-00002-5mg	In stock	Get quote
10 mg	USD 1,480.00	BP-00002-10mg	In stock	Get quote
50 mg	Inquire	BP-00002-50mg	In stock	Inquire
100 mg	Inquire	BP-00002-100mg	In stock	Inquire
1 g	Inquire	BP-00002-1g	In stock	Inquire

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Related forms

BP-00002A — Petrelintide acetate

Description

Petrelintide (ZP8396) is a dual amylin and calcitonin receptor agonist (DACRA) Petrelintide elicits a selective reduction in high-fat diet intake in diet-induced obese (DIO) rats, which is accompanied by a loss of fat mass and preservation of lean mass during weight reduction. Petrelintide can be utilized in diabetes research.

Biological activity

In Vitro Petrelintide demonstrates agonistic activity against hAMY3R and hCTR in HEK-293 cells, with EC50 of 2.997 and 9.215 nM, respectively.

Specifications

MW (average): 4191.6900 (free base)
Formula: C₁₈₅H₃₀₅N₄₉O₆₁
CAS No.: 2766385-23-1
Physical state: Solid
Color: White to off-white
Shipping: —
Storage: —

Solubility

DMSO : 25 mg/mL

Documents

References

[1]. Zong L, et al. Discovery of BGM1812, a Novel Dual Amylin and Calcitonin Receptor Agonist for Obesity Treatment. J Med Chem. 2025 Jul 24;68(14):14907-14918.

[2]. BILL V, et al. 1661-P: Petrelintide (ZP8396) Selectively Reduces Intake of High-Fat Diet in DIO Rats. Diabetes 14 June 2024; 73 (Supplement_1): 1661-P.

[3]. BILL V, et al. 1662-P: Petrelintide (ZP8396) Significantly Reduces Fat Mass while Preserving Lean Mass in DIO Rats. Diabetes 14 June 2024; 73 (Supplement_1): 1662-P.

[4]. JON G, et al. 1668-P: Novel Once-Weekly Amylin Analog Petrelintide (ZP8396) Is Well Tolerated with Improved GI Tolerability after Multiple Dosing, Diabetes, 2024;73(Supplement_1):1668-P

Same research area

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