Kif15 inhibitor 1 free base
Kif15-IN-1 is an inhibitor of the mitotic Kinesin family member 15 (Kif15), and is used for the research of cellular proliferative diseases.
For research use only. Not for human or veterinary use.
Target
Kinesin
Purity >98%
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Kif15 inhibitor 1 structure
CAS No.: 672926-32-8
Pack sizes & pricing
Description
Kif15-IN-1 is an inhibitor of the mitotic Kinesin family member 15 (Kif15), and is used for the research of cellular proliferative diseases.
Biological activity
In Vitro Kif15-IN-1 (Compound 10) is an inhibitor of the mitotic kinesin Hs Kif15, with the potential activities against cellular proliferative diseases such as cancer, hyperplasias, cardiac hypertrophy, immune disorders and inflammation
Identifiers
- SMILES
-
CCOC(=O)C1=C(N=C(S1)NC(=O)[C@H](C(C)C)N2C(=O)C3=CC=CC=C3NC2=O)C - InChIKey
-
CTQQKICGMSZCJL-AWEZNQCLSA-N
Specifications
- MW (average)
- 430.4770
- Formula
- C20H22N4O5S
- CAS No.
- 672926-32-8
- Physical state
- Solid
- Color
- White to off-white
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- Powder -20°C, 3 years , 4°C, 2 years; In solvent -20°C, 1 month;
Solubility
Soluble in DMSO
- In vitro
- DMSO : ≥ 100 mg/mL
Documents
References
[1]. Preparation of quinazolinediones as Kif15 kinesin inhibitors for treating cellular proliferative disorders. Pat. Appl. Publ. (2004), US 20040053948 A1 20040318.