DHX9-IN-2 free base · Synonyms: ATX-968 | ATX968

ATX968 is an inhibitor of ATP-dependent RNA helicase A.

For research use only. Not for human or veterinary use.

Target DHX9

Research area Cancer

Purity >98% Stock Inquire

Data Sheet SDS COA

DHX9-IN-2 structure

CAS No.: 2973395-71-8

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
250 mg	USD 621.00	BP-02267-250mg	In stock	Get quote
500 mg	USD 1,032.00	BP-02267-500mg	In stock	Get quote
1 g	USD 1,652.00	BP-02267-1g	In stock	Get quote
5 g	Inquire	BP-02267-5g	In stock	Inquire

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Description

ATX968 (example 31) is an inhibitor of ATP-dependent RNA helicase A (DHX9), with the EC50 of 0.054 μM in circBRIP1. ATX968 has antitumor activity.

Identifiers

SMILES: CC1=C(N=CC=C1)C2=CSC(=C2)C(=O)NC3=CC(=CC(=C3)Cl)NS(=O)(=O)C
InChIKey: VDGNPEFFHQRGOP-UHFFFAOYSA-N

Specifications

MW (average): 421.9210
Formula: C₁₈H₁₆ClN₃O₃S₂
CAS No.: 2973395-71-8
Physical state: Solid
Color: White to off-white
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder 4℃, 2 years; In solvent -20℃ 1 month;

Solubility

Soluble in DMSO

Documents

References

[1]. DANIELS Matthew H., et al. Preparation of imidazopyridines, thienopyrimidines, pyrrolopyrimidines and related heterocycles as inhibitors of RNA helicase DHX9 useful in treatment of cancers. World Intellectual Property Organization, WO2023154519 A1 2023-08-17

Same research area

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