iHSP110-33 free base · Synonyms: CPDA601356

iHSP110-33 is an inhibitor for heat shock protein 110 (HSP110).

For research use only. Not for human or veterinary use.

Target HSP STAT

Research area Cancer

Purity >98% Stock Inquire

Data Sheet SDS COA

iHSP110-33 structure

CAS No.: 1651890-48-0

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
50 mg	USD 850.00	BP-01918-50mg	In stock	Get quote
100 mg	USD 1,350.00	BP-01918-100mg	In stock	Get quote
250 mg	USD 2,380.00	BP-01918-250mg	In stock	Get quote
500 mg	USD 3,450.00	BP-01918-500mg	In stock	Get quote
1 g	Inquire	BP-01918-1g	In stock	Inquire

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Description

iHSP110-33 is an inhibitor for heat shock protein 110 (HSP110). iHSP110-33 exhibits antitumor efficacy agaisnt large B-cell lymphoma and classical Hodgkin lymphoma. iHSP110-33 shows a synergistic effect with Selinexor, inhibits the STAT6 phosphorylation, and enhances its antitumor activity[1].

Identifiers

SMILES: C(=C/C1=CC=CC=C1)\C2=C(N=CC(=C2)C3=CC(OC)=C(OC)C(OC)=C3)C=4C=C(C)C(=NC4)C5=CC(OC)=C(OC)C=C5
InChIKey: DBMGZVJHLSKVFA-OUKQBFOZSA-N

Specifications

MW (average): 574.6656
Formula: C₃₆H₃₄N₂O₅
CAS No.: 1651890-48-0
Physical state: Solid
Color: White to off-white
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month.

Solubility

Soluble in DMSO

Documents

References

[1]. Durand M, et al., A first-in-class inhibitor of HSP110 to potentiate XPO1-targeted therapy in primary mediastinal B-cell lymphoma and classical Hodgkin lymphoma. J Exp Clin Cancer Res. 2024 May 22;43(1):148.

Same target

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Same research area

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