PPZ-A10 free base

PPZ-A10 is an ionizable cationic lipid.

For research use only. Not for human or veterinary use.

Target Liposome

Research area Inflammation/Immunology Cancer

Purity >98% Stock Inquire

Data Sheet SDS COA

PPZ-A10 structure

CAS No.: 2941268-67-1

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
50 mg	USD 490.00	BP-02458-50mg	In stock	Get quote
100 mg	USD 780.00	BP-02458-100mg	In stock	Get quote
250 mg	USD 1,570.00	BP-02458-250mg	In stock	Get quote
500 mg	USD 2,500.00	BP-02458-500mg	In stock	Get quote
1 g	USD 4,010.00	BP-02458-1g	In stock	Get quote
2 g	Inquire	BP-02458-2g	In stock	Inquire

Need another size or custom synthesis? Request a quote.

Description

PPZ-A10 is an ionizable cationic lipid. PPZ-A10 preferentially delivers mRNA to liver and spleen immune cells. Pi-LNPs containing PPZ-A10 can effectively deliver mRNA/siRNA to solid tumors .

Identifiers

SMILES: O=C(CCN(CCCCCCCCCC)CCCCCCCCCC)NCCCN1CCN(CCCNC(CCN(CCCCCCCCCC)CCCCCCCCCC)=O)CC1
InChIKey: PXNLDSAGMDIEAT-UHFFFAOYSA-N

Specifications

MW (average): 903.5434
Formula: C₅₆H₁₁₄N₆O₂
CAS No.: 2941268-67-1
Physical state: Solid
Color: Light yellow to yellow
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month;

Solubility

Soluble in DMSO

Documents

References

[1].Ni H, et al. Piperazine-derived lipid nanoparticles deliver mRNA to immune cells in vivo. Nat Commun. 2022;13(1):4766.

[2]. Subhan MA, et al. Biopolymer-Based Nanosystems for siRNA Drug Delivery to Solid Tumors including Breast Cancer. Pharmaceutics. 2023 Jan 1;15(1):153.

Same research area

Search Inflammation/Immunology