SDH-IN-1 free base

SDH-IN-1 is a succinate dehydrogenase inhibitor.

For research use only. Not for human or veterinary use.

Target Fungal

Research area Infection

Purity >98% Stock Inquire

Data Sheet SDS COA

SDH-IN-1 structure

CAS No.: 2685795-52-0

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
250 mg	USD 550.00	BP-02379-250mg	In stock	Get quote
500 mg	USD 998.00	BP-02379-500mg	In stock	Get quote
1 g	USD 1,885.00	BP-02379-1g	In stock	Get quote
2 g	Inquire	BP-02379-2g	In stock	Inquire

Need another size or custom synthesis? Request a quote.

Description

SDH-IN-1 (compound 4i) is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 4.53 μM. SDH-IN-1 has potent antifungal activities. SDH-IN-1 displays potent activity against S. sclerotiorum (EC50 of 0.14 mg/L) .

Identifiers

SMILES: O=C(C1=NN=C(C2=CC=CS2)O1)NCC3=CC=C(Cl)C(Cl)=C3
InChIKey: VHRCPMTYUKLSDU-UHFFFAOYSA-N

Specifications

MW (average): 354.2110
Formula: C₁₄H₉Cl₂N₃O₂S
CAS No.: 2685795-52-0
Physical state: Solid
Color: White to off-white
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: 4°C, sealed storage, away from moisture and light

Solubility

Soluble in DMSO

In vitro: DMSO : 16.67 mg/mL

Documents

References

[1].Zihui Yang, et al. Design, Synthesis, and Antifungal Activity of Novel Thiophene/Furan-1,3,4-Oxadiazole Carboxamides as Potent Succinate Dehydrogenase Inhibitors. J Agric Food Chem. 2021 Nov 17;69(45):13373-13385.

Same target

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Same research area

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