Bifluranol free base · Synonyms: BX 341

Bifluranol (BX341) is an anti-androgen.

For research use only. Not for human or veterinary use.

Target Androgen Receptor

Research area Metabolic Disease

Purity >98% Stock Inquire

Data Sheet SDS COA

Bifluranol structure

CAS No.: 34633-34-6

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
50 mg	USD 800.00	BP-02066-50mg	In stock	Get quote
100 mg	USD 1,200.00	BP-02066-100mg	In stock	Get quote
250 mg	USD 1,700.00	BP-02066-250mg	In stock	Get quote
500 mg	Inquire	BP-02066-500mg	In stock	Inquire
1 g	Inquire	BP-02066-1g	In stock	Inquire

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Description

Bifluranol (BX341) is an anti-androgen.

Biological activity

In Vivo The absorption, distribution and excretion of Bifluranol have been studied in mouse, rat, ferret and dog; Bifluranol is readily absorbed following oral administration, but blood concentrations of Bifluranol are low due to hepatic uptake and biliary excretion. After intravenous administration of [3H]Bifluranol to rats (200 μg/kg) and ferrets (60 μg/kg) the blood concentrations of 3H decreases rapidly for the first 2 to 3 h, with the decrease being more rapid in females ( 18 min for rat, 30 min for ferret) than males (1.0 h for rat, 1.4 h for ferret). This is followed by a much slower decline (40 h for rat, 20 h for ferret) to concentrations at 96 h of less than 15 ng Bifluranol equivalents mL-1 (rat) or 1 ng Bifluranol equivalents mL-1 (ferret).

Identifiers

SMILES: C[C@H](C1=CC(F)=C(C=C1)O)[C@H](C2=CC(F)=C(C=C2)O)CC
InChIKey: RDVXUHOSYIBGBT-ZWNOBZJWSA-N

Specifications

MW (average): 292.3204
Formula: C₁₇H₁₈F₂O₂
CAS No.: 34633-34-6
Physical state: Solid
Color: white to off-white
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month

Solubility

Soluble in DMSO : 100 mg/mL

Documents

References

[1]. Pope DJ, et al. Bifluranol, a novel fluorinated bibenzyl anti-androgen, its chemistry and disposition in different animal species. J Pharm Pharmacol. 1981 May;33(5):297-301.

Same target

Search Androgen Receptor

Same research area

Search Metabolic Disease