VISTA-IN-3 free base · Synonyms: CPDP802334

VISTA-IN-3 is a potent VISTA small molecule inhibitor.

For research use only. Not for human or veterinary use.

Target IFNAR

Research area Cancer

Purity >98% Stock Inquire

Data Sheet SDS COA

VISTA-IN-3 structure

CAS No.: 2994662-45-0

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
50 mg	USD 520.00	BP-02062-50mg	In stock	Get quote
100 mg	USD 720.00	BP-02062-100mg	In stock	Get quote
250 mg	USD 1,020.00	BP-02062-250mg	In stock	Get quote
500 mg	Inquire	BP-02062-500mg	In stock	Inquire
1 g	Inquire	BP-02062-1g	In stock	Inquire

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Description

VISTA-IN-3 (Compound A4) is a potent VISTA small molecule inhibitor with a KD value of 0.49 μM. VISTA-IN-3 can induce the release of IFN-γ cytokines. VISTA-IN-3 synergistically enhances anti-cancer activity with PD-L1 antibody.

Identifiers

SMILES: OC1=CC=CC(NC2=NC(OC)=CC(CNCCO)=N2)=C1
InChIKey: KCTPHIOYWMANBF-UHFFFAOYSA-N

Specifications

MW (average): 290.3177
Formula: C₁₄H₁₈N₄O₃
CAS No.: 2994662-45-0
Physical state: Solid
Color: White to off-white
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month.

Solubility

Soluble in DMSO : 6.25 mg/mL

Documents

References

[1]. Sun C, He Y, et al. Design, Synthesis, and Antitumor Activity Evaluation of Novel VISTA Small Molecule Inhibitors. J Med Chem. 2024 Feb 27.

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