Bexicaserin free base · Synonyms: LP352 | CPDA601860
Bexicaserin is a 5-HT2C receptor agonist.
For research use only. Not for human or veterinary use.
Bexicaserin structure
CAS No.: 2035818-24-5
Pack sizes & pricing
| Size | Price | SKU | Stock | |
|---|---|---|---|---|
| 10 mg | USD 435.00 | BP-01961-10mg | Inquire | Get quote |
| 25 mg | USD 795.00 | BP-01961-25mg | Inquire | Get quote |
| 50 mg | USD 1,265.00 | BP-01961-50mg | Inquire | Get quote |
| 100 mg | USD 2,025.00 | BP-01961-100mg | Inquire | Get quote |
| 250 mg | Inquire | BP-01961-250mg | Inquire | Inquire |
Need another size or custom synthesis? Request a quote.
Description
Bexicaserin (LP352) is a 5-HT2C receptor agonist with potential for studying obesity and psychiatric-related disorders (such as epilepsy).
Biological activity
In Vitro Bexicaserin (10 µM, 24 or 48 hours) is a superagonist of the 5-HT2C receptor (a ligand that induces a greater response than the endogenous agonist), with a Ki of 44 nM. In dynamic mass redistribution (DMR) assays, Bexicaserin induced a maximal cellular response in HEK293 cells expressing the human 5-HT2C receptor that exceeded the response induced by the endogenous agonist 5-HT.
Identifiers
- SMILES
-
FC(F)CNC(C1=C2C3=C(C=C1)CNCCN3C[C@@H]2C)=O - InChIKey
-
KGOOOHQKLRUVSF-VIFPVBQESA-N
Specifications
- MW (average)
- 295.3277
- Formula
- C15H19F2N3O
- CAS No.
- 2035818-24-5
- Physical state
- Solid
- Color
- White to off-white
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- Powder 4°C, sealed storage, away from moisture and light; In solvent -20°C, 1 month.
Solubility
Soluble in DMSO : 50 mg/mL