KVD900 free base · Synonyms: Sebetralstat

Sebetralstat is a plasma kallikrein inhibitor.

For research use only. Not for human or veterinary use.

Target Kallikrein

Research area Metabolic Disease

Purity >98% Stock Inquire

Data Sheet SDS COA

KVD900 structure

CAS No.: 1933514-13-6

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
250 mg	USD 490.00	BP-01951-250mg	In stock	Get quote
500 mg	USD 710.00	BP-01951-500mg	In stock	Get quote
1 g	Inquire	BP-01951-1g	In stock	Inquire
2 g	Inquire	BP-01951-2g	In stock	Inquire
5 g	Inquire	BP-01951-5g	In stock	Inquire

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Description

Sebetralstat (KVD900) is a plasma kallikrein inhibitor (WO2016083820). Sebetralstat can be used for the research of metabolic diseases.

Biological activity

In Vitro Sebetralstat is a plasma kallikrein inhibitor[1].

Identifiers

SMILES: O=C(C1=CN(CC2=CC=C(CN3C=CC=CC3=O)C=C2)N=C1COC)NCC4=NC=CC(OC)=C4F
InChIKey: KGMPDQIYDKKXRD-UHFFFAOYSA-N

Specifications

MW (average): 491.5141
Formula: C₂₆H₂₆FN₅O₄
CAS No.: 1933514-13-6
Physical state: Solid
Color: White to off-white
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder -20℃ 2 years; In solvent -20℃ 1 month;

Solubility

Soluble in DMSO :≥ 125 mg/mL

Documents

References

[1]. WO2016083820

[2]. Maetzel, Andreas et al. “KVD900, an oral on-demand treatment for hereditary angioedema: Phase 1 study results.” The Journal of allergy and clinical immunology vol. 149,6 (2022): 2034-2042.

Same research area

Search Metabolic Disease